Preferred Label : retrograde degeneration;
MeSH definition : Pathologic changes that occur in the axon and cell body of a neuron proximal to an
axonal lesion. The process is characterized by central chromatolysis which features
flattening and displacement of the nucleus, loss of Nissl bodies, and cellular edema.
Central chromatolysis primarily occurs in lower motor neurons.;
MeSH synonym : axon reactions; degenerations, retrograde; nissl degeneration; reaction, axonal; retrograde degenerations; degeneration, retrograde; axonal reaction; axonal reactions; reactions, axonal; degeneration, nissl; axon reaction; reaction, axon; reactions, axon;
MeSH hyponym : retrograde degeneration, transneuronal; Degeneration, Transneuronal Retrograde; Degenerations, Transneuronal Retrograde; Retrograde Degenerations, Transneuronal; Transneuronal Retrograde Degeneration; Transneuronal Retrograde Degenerations; Trans-Synaptic Degeneration; Degeneration, Trans-Synaptic; Degenerations, Trans-Synaptic; Trans Synaptic Degeneration; Trans-Synaptic Degenerations;
Origin ID : D012183;
UMLS CUI : C0035354;
Allowable qualifiers
- Automatic exact mappings (from CISMeF team)
- Currated CISMeF NLP mapping
- Record concept(s)
- Semantic type(s)
- UMLS correspondences (same concept)
Pathologic changes that occur in the axon and cell body of a neuron proximal to an
axonal lesion. The process is characterized by central chromatolysis which features
flattening and displacement of the nucleus, loss of Nissl bodies, and cellular edema.
Central chromatolysis primarily occurs in lower motor neurons.
