Preferred Label : mink cell focus-inducing viruses;
MeSH definition : Strains of MURINE LEUKEMIA VIRUS discovered in 1976 by Hartley, Wolford, Old, and
Rowe and so named because the viruses originally isolated had the capacity to transform
cell foci in mink cell cultures. MCF viruses are generated by recombination with ecotropic
murine leukemia viruses including AKR, Friend, Moloney, and Rauscher, causing ERYTHROLEUKEMIA
and severe anemia in mice.;
MeSH synonym : mink cell focus-inducing virus; mink cell focus inducing virus; mcf virus; viruses, mcf; mcf viruses; virus, mcf; mink cell focus inducing viruses;
MeSH annotation : infection: coordinate IM with RETROVIRIDAE INFECTIONS (IM) TUMOR VIRUS INFECTIONS
(IM); add also LEUKEMIA, EXPERIMENTAL (IM), or LEUKEMIA (IM) (for spontaneous leukemia),
or ERYTHROLEUKEMIA (IM) if pertinent;
UNII : txid11785;
Origin ID : D008908;
UMLS CUI : C0026180;
Allowable qualifiers
Record concept(s)
Semantic type(s)
- Virus [UMLS semantic type]
Strains of MURINE LEUKEMIA VIRUS discovered in 1976 by Hartley, Wolford, Old, and
Rowe and so named because the viruses originally isolated had the capacity to transform
cell foci in mink cell cultures. MCF viruses are generated by recombination with ecotropic
murine leukemia viruses including AKR, Friend, Moloney, and Rauscher, causing ERYTHROLEUKEMIA
and severe anemia in mice.