Preferred Label : graft enhancement, immunologic;
MeSH definition : The induction of prolonged survival and growth of allografts of either tumors or normal
tissues which would ordinarily be rejected. It may be induced passively by introducing
graft-specific antibodies from previously immunized donors, which bind to the graft's
surface antigens, masking them from recognition by T-cells; or actively by prior immunization
of the recipient with graft antigens which evoke specific antibodies and form antigen-antibody
complexes which bind to the antigen receptor sites of the T-cells and block their
cytotoxic activity.;
MeSH synonym : enhancement, immunological graft; enhancements, immunological graft; immunological graft enhancement; enhancements, immunologic graft; graft enhancements, immunologic; immunologic enhancement of grafts; immunologic graft enhancement; enhancement, immunologic graft; graft enhancement, immunological; graft enhancements, immunological; immunologic graft enhancements; immunological graft enhancements;
MeSH Hyperonym : graft enhancement; Enhancement, Graft; Enhancements, Graft; Graft Enhancements;
MeSH annotation : to prevent graft rejection of normal or tumor tissue; do not coord with IMMUNOTHERAPY;
DF: GRAFT ENHANCEMENT;
Origin ID : D006082;
UMLS CUI : C0018127;
Allowable qualifiers
- Record concept(s)
- Semantic type(s)
The induction of prolonged survival and growth of allografts of either tumors or normal
tissues which would ordinarily be rejected. It may be induced passively by introducing
graft-specific antibodies from previously immunized donors, which bind to the graft's
surface antigens, masking them from recognition by T-cells; or actively by prior immunization
of the recipient with graft antigens which evoke specific antibodies and form antigen-antibody
complexes which bind to the antigen receptor sites of the T-cells and block their
cytotoxic activity.
