Preferred Label : freeze fracturing;
MeSH definition : Preparation for electron microscopy of minute replicas of exposed surfaces of the
cell which have been ruptured in the frozen state. The specimen is frozen, then cleaved
under high vacuum at the same temperature. The exposed surface is shadowed with carbon
and platinum and coated with carbon to obtain a carbon replica.;
MeSH synonym : fracturing, freeze; fracturings, freeze; freeze fracturings;
MeSH annotation : do not confuse with FREEZE ETCHING (wherein no cryoprotectant is used);
Origin ID : D005614;
UMLS CUI : C0016700;
Allowable qualifiers
- Record concept(s)
- Semantic type(s)
Preparation for electron microscopy of minute replicas of exposed surfaces of the
cell which have been ruptured in the frozen state. The specimen is frozen, then cleaved
under high vacuum at the same temperature. The exposed surface is shadowed with carbon
and platinum and coated with carbon to obtain a carbon replica.
