disulfiram - CISMeF

Preferred Label : disulfiram;

MeSH definition : A carbamate derivative used as an alcohol deterrent. It is a relatively nontoxic substance when administered alone, but markedly alters the intermediary metabolism of alcohol. When alcohol is ingested after administration of disulfiram, blood acetaldehyde concentrations are increased, followed by flushing, systemic vasodilation, respiratory difficulties, nausea, hypotension, and other symptoms (acetaldehyde syndrome). It acts by inhibiting aldehyde dehydrogenase.;

MeSH synonym : disulfide, tetraethylthiuram; tetraethylthioperoxydicarbonic diamide, ((h2n)c(s))2s2; tetraethylthiuram disulfide; bis(diethylthiocarbamoyl) disulfide;

CISMeF synonym : refusal; artu brand of disulfiram; allphar brand of disulfiram; altana pharma brand of disulfiram; bohm brand of disulfiram; dumex brand of disulfiram; odyssey brand of disulfiram; orphan brand of disulfiram; sanofi synthelabo brand of disulfiram;

MeSH hyponym : esperal; dicupral; antabuse; teturam; alcophobin; anticol; antabus;

MeSH CAS label : thioperoxydicarbonic diamide (((H2N)C(S))2S2), tetraethyl-;

MeSH Related Number : 97-77-8 (Disulfiram);

Registry Number MeSH : 97-77-8;

Wikipedia link : https://en.wikipedia.org/wiki/Disulfiram;

Codes EINECS : 202-607-8;

Is substance : O;

medicament (CISMeF) : O;

UNII : TR3MLJ1UAI;

InChIKey : AUZONCFQVSMFAP-UHFFFAOYSA-N;

Details

Origin ID

D004221;

UMLS CUI

C0012772;

ATC code(s)
- disulfiram [ATC Code]
- disulfiram, combinations [ATC Code]
ATC code(s)
- disulfiram [ATC Code]
- disulfiram [ATC Code]
- disulfiram, combinations [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Antabuse [ICHI extension code]
- Antabuse [ICD-11 Extension code]
- bis-(Diethylthiocarbamyl) disulfide (substance) [SNOMED CT concept]
- bis-(diethylthiocarbamyl) disulfide [SNOMED Notion]
CISMeF manual mappings
- Disulfiram adverse reaction (disorder) [SNOMED CT concept]
- Disulfiram measurement (procedure) [SNOMED CT concept]
- disulfiram [Substance BNPC]
Currated CISMeF NLP mapping
- Disulfiram [ICD-11 Extension code]
- Disulfiram [LOINC component]
- Disulfiram [ICHI extension code]
- Disulfiram [SMS substance]
- Disulfiram [NCIt concept]
- Disulfiram (substance) [SNOMED CT concept]
- Tetraethylthiuram disulfide [ICD-11 Extension code]
- Tetraethylthiuram disulfide [ICHI extension code]
- disulfiram [SNOMED Notion]
False automatic mappings
- Antabuse [PCS menu]
- Antabuse [PCS menu]
- Refuse [NCIt concept]
- Refused (qualifier value) [SNOMED CT concept]
- Trash [NCIt concept]
- Trash (qualifier value) [SNOMED CT concept]
Fils d'après SNOMED CT
- alcohol deterrents [MeSH Descriptor]
Pharmacological action(s)
- Acetaldehyde Dehydrogenase Inhibitors [MeSH Descriptor]
- alcohol deterrents [MeSH Descriptor]
Record concept(s)
- alcophobin [MeSH concept]
- antabus [MeSH concept]
- antabuse [MeSH concept]
- anticol [MeSH concept]
- dicupral [MeSH concept]
- disulfiram [MeSH concept]
- esperal [MeSH concept]
- teturam [MeSH concept]
Related MeSH Supplementary Concept(s)
- 4-methylpiperazino-thiuramdisulfide [MeSH Supplementary Concept]
- EWP 840 [MeSH Supplementary Concept]
- FLA 99 [MeSH Supplementary Concept]
- N,N,N',N'-tetraisopropylthiuram disulfide [MeSH Supplementary Concept]
- dimorpholinethiuram disulfide [MeSH Supplementary Concept]
- disulfiram-copper [MeSH Supplementary Concept]
- monosulfiram [MeSH Supplementary Concept]
- oterna [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Disulfiram [ICD-11 Extension code]
- Disulfiram [NCIt concept]
- Disulfiram [LOINC component]
- Disulfiram (substance) [SNOMED CT concept]
- Product containing disulfiram (medicinal product) [SNOMED CT concept]
- disulfiram [ATC Code]
- disulfiram [ATC Code]
- disulfiram [Substance BNPC]
- disulfiram [SNOMED Notion]
Validated automatic mappings to BTNT
- disulfiram [ATC Code]
- disulfiram [ATC Code]

Keyword's position in hierarchy(ies) :

Main resources

You can consult :

recommendations
documents concerning education
documents for patients