Preferred Label : disopyramide;

MeSH definition : A class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the heart similar to that of guanidine. It also possesses some anticholinergic and local anesthetic properties.;

MeSH synonym : diisopyramide;

MeSH hyponym : phosphate, disopyramide; monohydrochloride, disopyramide; norpace; disopyramide monohydrochloride; disopyramide phosphate (1:1), (R)-Isomer; disopyramide, L-Tartrate (1:1), (R)-Isomer; rhythmodan; disopyramide phosphate (1:1), ( -)-Isomer; Disopyramide Phosphate; disopyramide, D-Tartrate (1:1), (S)-Isomer; disopyramide, (R)-Isomer; palpitin; disopyramide, L-Tartrate (1:1), (S)-Isomer; disopyramide, L-Tartrate, (S)-isomer; disopyramide, (S)-Isomer; disopyramide, ( -)-Isomer; disopyramide phosphate (1:1), (S)-Isomer; SC-13957; disopyramide, L-Tartrate (1:2), ( -)-Isomer; ritmilen; Disopyramide Phosphate (1:1); Palpitine; Rythmilen; SC 13957; SC13957;

MeSH CAS label : 2-Pyridineacetamide, alpha-(2-(bis(1-methylethyl)amino)ethyl)-alpha-phenyl-;

MeSH Related Number : disopyramide, (S)-Isomer; disopyramide, D-Tartrate (1:1), (S)-Isomer; disopyramide, L-Tartrate (1:1), (R)-Isomer; disopyramide, L-Tartrate (1:1), (S)-Isomer; disopyramide, L-Tartrate (1:2), ( -)-Isomer; disopyramide, L-Tartrate, (S)-isomer; disopyramide monohydrochloride; disopyramide phosphate; disopyramide phosphate (1:1), ( -)-Isomer; disopyramide phosphate (1:1), (R)-Isomer; disopyramide phosphate (1:1), (S)-Isomer; disopyramide, ( -)-Isomer; disopyramide, (R)-Isomer; 22059-60-5 (Disopyramide phosphate); 3737-09-5 (Disopyramide); 108609-26-3; 54687-36-4; 74427-45-5; 74427-46-6; 74464-83-8; 74464-84-9; 74497-00-0; 79190-73-1; 79200-58-1; 79200-59-2; 87367-28-0; 87367-29-1; N6BOM1935W;

Registry Number MeSH : 3737-09-5;

Related CAS MeSH : 74427-45-5 (Disopyramide, ( -)-Isomer); 74497-00-0 (Disopyramide, D-Tartrate (1:1), (S)-Isomer); 87367-28-0 (Disopyramide, L-Tartrate (1:1), (R)-Isomer); 87367-29-1 (Disopyramide, L-Tartrate (1:1), (S)-Isomer); 74427-46-6 (Disopyramide, L-Tartrate (1:2), ( -)-Isomer); 108609-26-3 (Disopyramide, L-Tartrate, (S)-isomer); 54687-36-4 (Disopyramide monohydrochloride); 79190-73-1 (Disopyramide phosphate (1:1), ( -)-Isomer); 79200-59-2 (Disopyramide phosphate (1:1), (R)-Isomer); 79200-58-1 (Disopyramide phosphate (1:1), (S)-Isomer); 74464-83-8 (Disopyramide, (R)-Isomer); 74464-84-9 (Disopyramide, (S)-Isomer); N6BOM1935W (Disopyramide phosphate);

Wikipedia link : https://en.wikipedia.org/wiki/Disopyramide;

Codes EINECS : 223-110-2;

Is substance : O;

UNII : GFO928U8MQ;

InChIKey : UVTNFZQICZKOEM-UHFFFAOYSA-N;

Details


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A class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the heart similar to that of guanidine. It also possesses some anticholinergic and local anesthetic properties.

https://ansm.sante.fr/actualites/tensions-dapprovisionnement-en-rythmodan-250-mg-lp-disopyramide-recommandations-pour-les-pharmaciens-et-les-medecins
2025
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drug information
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disopyramide
Disopyramide Phosphate
Delayed-Action preparations
disopyramide
anti-arrhythmia agents

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https://ansm.sante.fr/actualites/difficultes-dapprovisionnement-en-rythmodan-250-mg-lp-ce-medicament-doit-etre-remplace-par-rythmodan-100-mg
2024
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guideline
drug information
disopyramide
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administration, oral
anti-arrhythmia agents
patient education handout

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https://ansm.sante.fr/disponibilites-des-produits-de-sante/medicaments/rythmodan-250-mg-a-liberation-prolongee-comprime-enrobe-disopyramide-phosphate-de
2024
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disopyramide
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https://www.has-sante.fr/jcms/p_3210100/fr/isorythm-lp
2020
false
false
false
France
French
treatment outcome
insurance, health, reimbursement
evaluation of the transparency committee
Substance Abuse, Oral
Disopyramide Phosphate
anti-arrhythmia agents
disopyramide
recurrence
tachycardia, supraventricular
Ventricular Arrhythmia
Ventricular Arrhythmia
disopyramide

---
https://www.has-sante.fr/jcms/p_3210121/fr/rythmodan
2020
false
false
false
France
French
treatment outcome
insurance, health, reimbursement
administration, oral
evaluation of the transparency committee
disopyramide
recurrence
tachycardia, supraventricular
anti-arrhythmia agents
Ventricular Arrhythmia
Ventricular Arrhythmia
disopyramide

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https://www.hc-sc.gc.ca/dhp-mps/medeff/bulletin/hpiw-ivps_2016-12-page2-fra.php#ryth
2016
false
false
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Canada
French
English
pharmacovigilance note
agranulocytosis
disopyramide

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http://www.has-sante.fr/portail/display.jsp?id=c_632358
http://www.has-sante.fr/portail/jcms/c_1670221/fr/isorythm
http://www.has-sante.fr/portail/jcms/c_1670220/fr/isorythm-16102013-avis-ct12951
2013
France
French
secondary prevention
disopyramide
anti-arrhythmia agents
administration, oral
Delayed-Action preparations
insurance, health, reimbursement
arrhythmias, cardiac
tachycardia, supraventricular
ventricular arrhythmia, nos
disopyramide
capsules
evaluation of the transparency committee
Disopyramide Phosphate

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http://www.has-sante.fr/portail/jcms/c_1352605/rythmodan
http://www.has-sante.fr/portail/jcms/c_1352604/rythmodan-19122012-avis-ct12326
http://www.has-sante.fr/portail/display.jsp?id=c_400340
http://www.has-sante.fr/portail/display.jsp?id=c_631270
2012
false
France
French
secondary prevention
Delayed-Action preparations
disopyramide
insurance, health, reimbursement
disopyramide
anti-arrhythmia agents
administration, oral
evaluation of the transparency committee
Ventricular arrhythmia
arrhythmias, cardiac
arrhythmias, cardiac
tachycardia, supraventricular
electric countershock

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