Cytochrome P-450 CYP2J2

Preferred Label : Cytochrome P-450 CYP2J2;

MeSH definition : A cytochrome P450 enzyme involved in oxidizing POLYUNSATURATED FATTY ACIDS (PUFA) to PUFA epoxides which function as potent lipid mediators. This enzyme, encoded by CYP2J2 gene, metabolizes ARACHIDONIC ACID to epoxyeicosatrienoic acids (EETs) which produce biological effects including VASODILATION.;

MeSH synonym : Cytochrome P 450 CYP2J2; CYP2J2;

MeSH Hyperonym : Epoxygenase, Arachidonate; Cytochrome P-450 Epoxygenase; Cytochrome P-450 Arachidonate Oxygenase; Cytochrome P 450 Arachidonate Oxygenase; NADPH-Dependent Arachidonic Acid Epoxygenase; NADPH Dependent Arachidonic Acid Epoxygenase; Arachidonic Acid Epoxygenase; Acid Epoxygenase, Arachidonic; Epoxygenase, Arachidonic Acid;

UNII : EC 1.14.14.1;

Details

Origin ID

D000090762;

UMLS CUI

C0377773;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Cytochrome p450, subfamily iij, polypeptide 2 [OMIM gene]
Currated CISMeF NLP mapping
- Cytochrome p450 CYP2J2 enzyme (substance) [SNOMED CT concept]
Record concept(s)
- arachidonate epoxygenase [MeSH concept]
- cytochrome P-450 CYP2J2 [MeSH concept]
Related MeSH Supplementary Concept(s)
- CYP2J2 protein, human [MeSH Supplementary Concept]
- Cyp2c23 protein, rat [MeSH Supplementary Concept]
- Cyp2j5 protein, mouse [MeSH Supplementary Concept]
- Cyp2j6 protein, mouse [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Cytochrome p450 CYP2J2 enzyme (substance) [SNOMED CT concept]

Keyword's position in hierarchy(ies) :

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