Preferred Label : Antigenic Drift and Shift;
MeSH definition : Changes in the ANTIGEN population by slow and minor (antigenic drift) or sudden and
major mutations (antigenic shift). Accumulation of minor mutations in antigenic drift
over time may require development of new vaccine (e.g., seasonal FLU VACCINES). Antigenic
shift on the other hand is less common but may result in emergence of a new subtype
or species and sometimes pandemics (e.g., H1N1 pandemics in 2009 and 2018 and COVID-19)
due to lack of HERD IMMUNITY to the newly emerged novel pathogen.;
MeSH synonym : Antigenic Shift and Drift; Antigen Shift and Drift; Antigen Drift and Shift;
MeSH hyponym : Shift, Antigenic; Antigen Shift; Shift, Antigen; Escape, Antigenic; Antigen Escape; Escape, Antigen; Drift, Antigenic; Antigen Drift; Drift, Antigen;
Origin ID : D000088603;
UMLS CUI : C5544391;
Allowable qualifiers
- Record concept(s)
- Semantic type(s)
Changes in the ANTIGEN population by slow and minor (antigenic drift) or sudden and
major mutations (antigenic shift). Accumulation of minor mutations in antigenic drift
over time may require development of new vaccine (e.g., seasonal FLU VACCINES). Antigenic
shift on the other hand is less common but may result in emergence of a new subtype
or species and sometimes pandemics (e.g., H1N1 pandemics in 2009 and 2018 and COVID-19)
due to lack of HERD IMMUNITY to the newly emerged novel pathogen.
