Promyelocytic Leukemia Nuclear Bodies

Preferred Label : Promyelocytic Leukemia Nuclear Bodies;

MeSH definition : Spherical intranuclear membraneless bodies nucleated by PROMYELOCYTIC LEUKEMIA PROTEIN and various other proteins containing small ubiquitin-related modifier (SUMO) interaction motif (SIM) and/or sumoylated proteins (e.g., Sp100 protein). Promyelocytic leukemia nuclear bodies regulate posttranslational modifications of partner proteins (e.g., SUMOYLATION) which in turn lead to modulation of various biological processes.;

MeSH synonym : Promyelocytic Leukemia Protein Bodies; PML NBs; Promyelocytic Leukemia Protein Body; PML Bodies; PML Body; Promyelocytic Leukemia Nuclear Body; PML Nuclear Bodies; Nuclear Bodies, PML; Nuclear Body, PML; PML Nuclear Body;

Details

Origin ID

D000088182;

UMLS CUI

C1167110;

Allowable qualifiers
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- enzymology [MeSH Qualifier]
- genetics [MeSH Qualifier]
- immunology [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- microbiology [MeSH Qualifier]
- parasitology [MeSH Qualifier]
- pathology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- transplantation [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- virology [MeSH Qualifier]
Currated CISMeF NLP mapping
- PML body [GO term]
Record concept(s)
- Promyelocytic Leukemia Nuclear Bodies [MeSH concept]
Semantic type(s)
- Cell Component [UMLS semantic type]
UMLS correspondences (same concept)
- PML body [GO term]

Keyword's position in hierarchy(ies) :

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