Gingipain Cysteine Endopeptidases

Preferred Label : Gingipain Cysteine Endopeptidases;

MeSH definition : Cysteine endoproteinases, from periodontal pathogen PORPHYROMONAS GINGIVALIS, acting as virulence factors associated with PERIODONTITIS. They are produced as pre-proproteins which mature into ARGININE and LYSINE specific endopeptidases.;

MeSH synonym : Cysteine Endopeptidases, Gingipain; Gingipain Proteases; Gingipains; Gingipain;

MeSH hyponym : Gingipain R1; Arginine Gingipain; Gingipain, Arginine; Arg-Gingipain; Arg Gingipain; Argingipain; RGPB Protein; RGP-2 Gingipain; Gingipain, RGP-2; RGP 2 Gingipain; KGP Protease; Lys-Gingipain; Lys Gingipain; Lysine Gingipain; Gingipain, Lysine;

MeSH Related Number : 3HJ2M2X2UM; EC 3.4.22.-; EC 3.4.22.37; EC 3.4.22.47;

Wikipedia link : https://en.wikipedia.org/wiki/Argingipain;

Details

Origin ID

D000080867;

UMLS CUI

C5197759;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Record concept(s)
- Gingipain Cysteine Endopeptidases [MeSH concept]
- Gingipain K [MeSH concept]
- Gingipain R [MeSH concept]
- Gingipain R2 [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
Validated automatic mappings to BTNT
- Gingipain R (substance) [SNOMED CT concept]

Keyword's position in hierarchy(ies) :

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