Preferred Label : WW Domains;
MeSH definition : An approximately 40 amino acid protein domain that occurs in a variety of unrelated
proteins and may be repeated up to four times in some proteins. It is characterized
by two TRYPTOHAN residues (WW) about 20 amino acids apart and folds into a stable
triple-stranded BETA-SHEET. It binds PROLINE-RICH PROTEIN DOMAINS and PHOSPHOSERINE
or PHOSPHOTHREONINE-containing protein domains that occur in many signal transducing
and cytoskeletal proteins, such as DYSTROPHIN.; An approximately 40 amino acid protein domain that occurs in a variety of unrelated
proteins and may be repeated up to four times in some proteins. It is characterized
by two TRYPTOPHAN residues (WW) about 20 amino acids apart and folds into a stable
triple-stranded BETA-SHEET. It binds PROLINE-RICH PROTEIN DOMAINS and PHOSPHOSERINE
or PHOSPHOTHREONINE-containing protein domains that occur in many signal-transducing
and cytoskeletal proteins such as DYSTROPHIN.;
MeSH synonym : WW Domain; Domain, WW; Domains, WW;
Origin ID : D000074585;
UMLS CUI : C4505249;
Allowable qualifiers
- Record concept(s)
- Semantic type(s)
An approximately 40 amino acid protein domain that occurs in a variety of unrelated
proteins and may be repeated up to four times in some proteins. It is characterized
by two TRYPTOHAN residues (WW) about 20 amino acids apart and folds into a stable
triple-stranded BETA-SHEET. It binds PROLINE-RICH PROTEIN DOMAINS and PHOSPHOSERINE
or PHOSPHOTHREONINE-containing protein domains that occur in many signal transducing
and cytoskeletal proteins, such as DYSTROPHIN.
An approximately 40 amino acid protein domain that occurs in a variety of unrelated
proteins and may be repeated up to four times in some proteins. It is characterized
by two TRYPTOPHAN residues (WW) about 20 amino acids apart and folds into a stable
triple-stranded BETA-SHEET. It binds PROLINE-RICH PROTEIN DOMAINS and PHOSPHOSERINE
or PHOSPHOTHREONINE-containing protein domains that occur in many signal-transducing
and cytoskeletal proteins such as DYSTROPHIN.
