Preferred Label : A549 Cells;
MeSH definition : An immortalized cell line derived from human ADENOCARCINOMA, ALVEOLAR basal epithelial
cells isolated from the lungs of a male patient in 1972. The cell line is positive
for KERATIN, can synthesize LECITHIN, and contains high levels of POLYUNSATURATED
FATTY ACIDS in its PLASMA MEMBRANE. It is used as a model for PULMONARY ALVEOLI function
and virus infections, as a TRANSFECTION host, and for PRECLINICAL DRUG EVALUATION.;
MeSH synonym : A549 Cell; Cell, A549; Cells, A549; A549 Cell Line; A549 Cell Lines; Cell Line, A549; Cell Lines, A549;
MeSH annotation : almost always NIM with no subheadings; check HUMAN; do not routinely add ADENOCARCINOMA,
ALVEOLAR;
Origin ID : D000072283;
UMLS CUI : C4277577;
Allowable qualifiers
Record concept(s)
Semantic type(s)
- Cell [UMLS semantic type]
An immortalized cell line derived from human ADENOCARCINOMA, ALVEOLAR basal epithelial
cells isolated from the lungs of a male patient in 1972. The cell line is positive
for KERATIN, can synthesize LECITHIN, and contains high levels of POLYUNSATURATED
FATTY ACIDS in its PLASMA MEMBRANE. It is used as a model for PULMONARY ALVEOLI function
and virus infections, as a TRANSFECTION host, and for PRECLINICAL DRUG EVALUATION.