Fertilins - CISMeF

Preferred Label : Fertilins;

MeSH definition : Sperm surface proteins involved in sperm-egg fusion. They consist of two subunits, fertilin alpha (ADAM1a) and beta (ADAM2), both of which belong to the metalloprotease-disintegrin protein family. The beta subunit does not have catalytic activity.;

MeSH synonym : Fertilin Protein; PH-30 Fusion Protein; PH-30 Protein; PH 30 Protein; Fertilin; PH 30 Fusion Protein;

DeCS synonym : Fertilin beta; Fertilin alpha;

MeSH hyponym : alpha, Fertilin; ADAM 1a Protein; ADAM1a Protein; PH-30 alpha; PH 30 alpha; alpha, PH-30; ADAM1 Protein; beta, Fertilin; ADAM 2 Protein; ADAM2 Protein; PH-30 beta; PH 30 beta; beta, PH-30;

Registry Number MeSH : EC 3.4.24.-;

Details

Origin ID

D000072196;

UMLS CUI

C0166429;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- A disintegrin and metalloproteinase domain 2 [OMIM gene]
- ADAM metallopeptidase domain 1A (pseudogene) [HGNC gene]
Record concept(s)
- Fertilins [MeSH concept]
- fertilin alpha [MeSH concept]
- fertilin beta [MeSH concept]
Related MeSH Supplementary Concept(s)
- ADAM2 protein, human [MeSH Supplementary Concept]
- Adam1a protein, mouse [MeSH Supplementary Concept]
- Adam1a protein, rat [MeSH Supplementary Concept]
- Adam1b protein, mouse [MeSH Supplementary Concept]
- Adam2 protein, mouse [MeSH Supplementary Concept]
- Adam2 protein, rat [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients