Preferred Label : Death Domain Superfamily;
MeSH definition : A family of structurally-related protein interaction domains characterized by 6-helical
closed bundle fold, with Greek key topology and an internal pseudo two-fold symmetry.
Death-like domains occur in many proteins that are essential for APOPTOSIS, including
CASPASE RECRUITMENT DOMAIN CONTAINING PROTEINS and DEATH DOMAIN RECEPTORS.;
MeSH synonym : Death Domain Superfamilies; Domain Superfamilies, Death; Domain Superfamily, Death; Superfamilies, Death Domain; Superfamily, Death Domain; Death-Like Domains; Death Like Domains; Death-Like Domain; Death Like Domain;
Origin ID : D000071458;
UMLS CUI : C4277614;
Allowable qualifiers
Record concept(s)
Semantic type(s)
A family of structurally-related protein interaction domains characterized by 6-helical
closed bundle fold, with Greek key topology and an internal pseudo two-fold symmetry.
Death-like domains occur in many proteins that are essential for APOPTOSIS, including
CASPASE RECRUITMENT DOMAIN CONTAINING PROTEINS and DEATH DOMAIN RECEPTORS.