NCIt definition : A synthetic 4-azasteroid compound. Finasteride competitively binds to and inhibits
steroid type II 5-alpha-reductase in the prostate gland, liver, and skin, thereby
interfering with the enzymatic conversion of testosterone to 5-dihydrotestosterone
(DHT) and reducing serum DHT levels. The reduction in serum DHT levels results in
diminished stimulation of androgen receptors in the nuclei of prostate cells and,
so, diminished prostate cell proliferation.;
Alternative definition : NCI-GLOSS: A drug used to reduce the amount of male hormone (testosterone) produced
by the body.;
UNII : 57GNO57U7G;
InChIKey : DBEPLOCGEIEOCV-WSBQPABSSA-N;
CAS number : 98319-26-7;
Drug name : Proscar; Prostide; Pro-Cure; Finastid; Chibro-Proscar; Urprosan; Propecia; Propeshia;