" /> Posoleucel - CISMeF





Preferred Label : Posoleucel;

NCIt synonyms : Allogeneic EBV/CMV/AdV/HHV6/BKV/JCV-specific CTLs ALVR105; Allogeneic Multi-virus-specific CTLs ALVR105; VSTs ALVR105;

NCIt definition : A population of closely human leukocyte antigen (HLA)-matched, off-the-shelf (OTS), donor-derived cytotoxic T lymphocytes (CTLs) that are specifically reactive towards six viruses, Epstein-Barr virus (EBV), cytomegalovirus (CMV), adenovirus (AdV), human herpesvirus 6 (HHV6; HHV-6), human polyomavirus type I (BKV) and human polyomavirus type II (JC virus; JCV), with potential antiviral activity. Upon infusion into allogeneic hematopoietic stem cell transplant (HSCT) recipients and immunocompromised patients, posoleucel provides virus-specific cellular immunity and causes specific anti-viral effects against active viral infections. This may prevent EBV, CMV, AdV, HHV6, BKV and JCV reactivation and infection, and inhibits viral-associated diseases.;

UNII : CH357NR3E3;

Drug name : Viralym-M;

Molecule name : ALVR-105; ALVR 105;

NCI Metathesaurus CUI : CL1406864;

Details


You can consult :


Nous contacter.
14/07/2025


[Home] [Top]

© Rouen University Hospital. Any partial or total use of this material must mention the source.