cystathionine beta-Synthase

Preferred Label : cystathionine beta-Synthase;

MeSH definition : A multifunctional pyridoxal phosphate enzyme. In the second stage of cysteine biosynthesis it catalyzes the reaction of homocysteine with serine to form cystathionine with the elimination of water. Deficiency of this enzyme leads to HYPERHOMOCYSTEINEMIA and HOMOCYSTINURIA. EC 4.2.1.22.;

MeSH synonym : serine sulfhydrase; beta-thionase; beta thionase; sulfhydrase, serine; cystathionine synthetase; synthetase, cystathionine; beta-synthase, cystathionine; cystathionine beta synthase;

MeSH CAS label : L-Serine hydro-lyase (adding homocysteine);

MeSH Related Number : 9023-99-8 (CAS RN);

Registry Number MeSH : EC 4.2.1.22;

MeSH annotation : /defic: consider also HOMOCYSTINURIA or HYPERHOMOCYSTEINEMIA;

Is substance : O;

UNII : EC 4.2.1.22;

Details

Origin ID

D003541;

UMLS CUI

C0010641;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- Cystathionine beta synthase [LOINC component]
- Cystathionine beta-synthase (substance) [SNOMED CT concept]
- cystathionine beta-synthase [SNOMED Notion]
Record concept(s)
- cystathionine beta-Synthase [MeSH concept]
Related MeSH Supplementary Concept(s)
- CBSX2 protein, arabidopsis [MeSH Supplementary Concept]
- CDCP2 protein, arabidopsis [MeSH Supplementary Concept]
- Cbs protein, mouse [MeSH Supplementary Concept]
See also
- homocystinuria [MeSH Descriptor]
See also (suggested by CISMeF)
- hyperhomocysteinemia [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Cystathionine beta synthase [LOINC component]
- Cystathionine beta-synthase (substance) [SNOMED CT concept]
- cystathionine beta-synthase [SNOMED Notion]

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