Preferred Label : CYP2C9*16 Allele;
NCIt synonyms : CYP2C9, c.895A G; CYP2C9, c.895A G; CYP2C9, c.895A G; CYP2C9, T299A; CYP2C9*16; Cytochrome P450, Family 2, Subfamily C, Polypeptide 9*16 Allele; CYP2C9 16 Allele;
NCIt definition : Human CYP2C9*16 allele is located within 10q24 and is approximately 33 kb in length.
This allele, a variant form of the CYP2C9 wild-type allele, encodes cytochrome P450
2C9*16 protein. The CYP2C9*16 allele exhibits a clinically-relevant SNP (c.895A G)
that results in a T299A coding change. This alteration in protein sequence decreases
the in vivo enzymatic activity of the cytochrome P450 2C9*16 protein.; Human CYP2C9*16 allele is located within 10q24 and is approximately 33 kb in length.
This allele, a variant form of the CYP2C9 wild-type allele, encodes cytochrome P450
2C9*16 protein. The CYP2C9*16 allele exhibits a clinically-relevant SNP (c.895A G)
that results in a T299A coding change. This alteration in protein sequence decreases
the in vivo enzymatic activity of the cytochrome P450 2C9*16 protein.; Human CYP2C9*16 allele is located within 10q24 and is approximately 33 kb in length.
This allele, a variant form of the CYP2C9 wild-type allele, encodes cytochrome P450
2C9*16 protein. The CYP2C9*16 allele exhibits a clinically-relevant SNP (c.895A G)
that results in a T299A coding change. This alteration in protein sequence decreases
the in vivo enzymatic activity of the cytochrome P450 2C9*16 protein.;
NCIt note : Ethnicity Association: Asian;
GenBank Accession Number : NM_000771;
PubMed : 15371982;
Origin ID : C46018;
UMLS CUI : C1707199;
OMIM relation
- Semantic type(s)
- allele_has_abnormality
- allele_has_activity
- allele_in_chromosomal_location
- allele_plays_altered_role_in_process
- concept_is_in_subset
- gene_found_in_organism
- gene_plays_role_in_process
