Uberon definition : Brodmann area 12 is a subdivision of the cerebral cortex of the guenon defined on
the basis of cytoarchitecture. It occupies the most rostral portion of the frontal
lobe. Brodmann-1909 did not regard it as homologous, either topographically or cytoarchitecturally,
to rostral area 12 of the human. Distinctive features (Brodmann-1905): a quite distinct
internal granular layer (IV) separates slender pyramidal cells of the external pyramidal
layer (III) and the internal pyramidal layer (V); the multiform layer (VI) is expanded,
contains widely dispersed spindle cells and merges gradually with the underlying cortical
white matter; all cells, including the pyramidal cells of the external and internal
pyramidal layers are inordinately small; the internal pyramidal layer (V) also contains
spindle cells in groups of two to five located close to its border with the internal
granular layer (IV).;
Uberon synonym : frontopolar area; Brodmann area 12, prefrontal; Brodmann area 12; B09-12; area 12 of Brodmann-1909; area 12 of Brodmann; area praefrontalis;
Brodmann area 12 is a subdivision of the cerebral cortex of the guenon defined on
the basis of cytoarchitecture. It occupies the most rostral portion of the frontal
lobe. Brodmann-1909 did not regard it as homologous, either topographically or cytoarchitecturally,
to rostral area 12 of the human. Distinctive features (Brodmann-1905): a quite distinct
internal granular layer (IV) separates slender pyramidal cells of the external pyramidal
layer (III) and the internal pyramidal layer (V); the multiform layer (VI) is expanded,
contains widely dispersed spindle cells and merges gradually with the underlying cortical
white matter; all cells, including the pyramidal cells of the external and internal
pyramidal layers are inordinately small; the internal pyramidal layer (V) also contains
spindle cells in groups of two to five located close to its border with the internal
granular layer (IV).