Uberon definition : The rhombencephalon (or hindbrain) is a developmental categorization of portions of
the central nervous system in vertebrates. The rhombencephalon can be subdivided in
a variable number of transversal swellings called rhombomeres. In the human embryo
eight rhombomeres can be distinguished, from caudal to rostral: Rh7-Rh1 and the isthmus
(the most rostral rhombomere). A rare disease of the rhombencephalon, 'rhombencephalosynapsis'
is characterized by a missing vermis resulting in a fused cerebellum. Patients generally
present with cerebellar ataxia. The caudal rhombencephalon has been generally considered
as the initiation site for neural tube closure.;
Uberon synonym : presumptive rhombencephalon;
Uberon related term : embryonic rhombencephalon; future hindbrain; rhombencephalon;
The rhombencephalon (or hindbrain) is a developmental categorization of portions of
the central nervous system in vertebrates. The rhombencephalon can be subdivided in
a variable number of transversal swellings called rhombomeres. In the human embryo
eight rhombomeres can be distinguished, from caudal to rostral: Rh7-Rh1 and the isthmus
(the most rostral rhombomere). A rare disease of the rhombencephalon, 'rhombencephalosynapsis'
is characterized by a missing vermis resulting in a fused cerebellum. Patients generally
present with cerebellar ataxia. The caudal rhombencephalon has been generally considered
as the initiation site for neural tube closure.