Preferred Label : chordo neural hinge;
Uberon definition : Portion of tissue that is posterior to the developing notochord during tail bud extension.;
Uberon synonym : CNH; chordoneural hinge;
Uberon Homology note : Although there is mounting evidence showing the comparability of events and formation
of different nascent tissue types during gastrulation and tail development, recent
work also suggests the presence of an ongoing stem cell population capable of contributing
to multiple tissue types in the tail of several different vertebrates, situated in
the chordoneural hinge region of the tail bud. It would seem likely that secondary
signaling centers regulate the fate to be adopted by such pluripotent progenitors.[well
established][VHOG];
Uberon Taxon note : In mouse and chick, the derivative of the NSB (with a minor contribution from the
CLE), the chordo-neural-hinge'(CNH) (Cambray and Wilson, 2007; Catala et al., 1995;
Charrier et al., 1999), contains progenitors for the ventral neural tube, somites
and notochord (Cambray and Wilson, 2002; McGrew et al., 2008). The CNH is continuous
with the most recently formed neural tube and notochord. By contrast, the tissue immediately
caudal to the CNH exclusively produces somites in mouse and chick (McGrew et al.,
2008).;
Origin ID : 0007097;
Automatic exact mappings (from CISMeF team)
- part of
Portion of tissue that is posterior to the developing notochord during tail bud extension.
