Preferred Label : aortico-pulmonary spiral septum;
Uberon definition : The spiral septum that separates the truncus arteriosus into a ventral pulmonary trunk
and the dorsal aorta[MP]. The aorticopulmonary septum is developmentally formed from
neural crest, specifically the cardiac neural crest, and actively separates the aorta
and pulmonary arteries and fuses with the interventricular septum within the heart
during development. The actual mechanism of septation of the outflow tract is poorly
understood, but is recognized as a dynamic process with contributions from contractile,
hemodynamic, and extracellular matrix interactions.;
Uberon synonym : aorticopulmonary septum; aortico-pulmonary septum;
Uberon related term : aortic septum; spiral septum;
Origin ID : 0006207;
Automatic exact mappings (from CISMeF team)
- adjacent to
- develops from
The spiral septum that separates the truncus arteriosus into a ventral pulmonary trunk
and the dorsal aorta[MP]. The aorticopulmonary septum is developmentally formed from
neural crest, specifically the cardiac neural crest, and actively separates the aorta
and pulmonary arteries and fuses with the interventricular septum within the heart
during development. The actual mechanism of septation of the outflow tract is poorly
understood, but is recognized as a dynamic process with contributions from contractile,
hemodynamic, and extracellular matrix interactions.
