Uberon Homology note : The mature AV (atrioventricular) valve of the adult zebrafish 2-chambered heart is
structurally similar to the mammalian AV valves with stratified ECM (extracellular
matrix) and supporting chordae tendineae. Therefore, the major cellular and molecular
events of valve development are largely conserved among animals with hearts composed
of multiple chambers.[uncertain][VHOG];