Preferred Label : chorioallantoic membrane;
Uberon definition : The chorioallantoic membrane is a vascular membrane found in eggs of some amniotes,
such as birds and reptiles. It is formed by the fusion of the mesodermal layers of
two developmental structures: the allantois and the chorion. Three different layers
compose the chorioallantoic membrane; these are called the chorionic epithelium, the
mesenchyme and the allantoic epithelium. Blood capillaries and sinuses are found between
epithelial cells of the chorionic layer, allowing close contact (within 0.2 N m) with
air found in pores of the shell membrane of the egg. As a result, the chorioallantoic
membrane allows exchange of gases, such as oxygen, to developing embryos. During embryonic
development of birds, the chorioallantoic membrane also plays an essential role in
bone formation by transporting calcium into the embryo from the eggshell. Chorioalloantoic
membranes from developing chicken eggs are routinely used in biological and biomedical
research to investigate development, angiogenesis, tumors, and to propagate and investigate
viruses or helminths.;
Uberon synonym : chorioallantois;
Uberon broad term : respiratory membrane;
Origin ID : 0005335;
UMLS CUI : C0178551;
Automatic exact mappings (from CISMeF team)
Semantic type(s)
UMLS correspondences (same concept)
Uberon cross reference
develops from
The chorioallantoic membrane is a vascular membrane found in eggs of some amniotes,
such as birds and reptiles. It is formed by the fusion of the mesodermal layers of
two developmental structures: the allantois and the chorion. Three different layers
compose the chorioallantoic membrane; these are called the chorionic epithelium, the
mesenchyme and the allantoic epithelium. Blood capillaries and sinuses are found between
epithelial cells of the chorionic layer, allowing close contact (within 0.2 N m) with
air found in pores of the shell membrane of the egg. As a result, the chorioallantoic
membrane allows exchange of gases, such as oxygen, to developing embryos. During embryonic
development of birds, the chorioallantoic membrane also plays an essential role in
bone formation by transporting calcium into the embryo from the eggshell. Chorioalloantoic
membranes from developing chicken eggs are routinely used in biological and biomedical
research to investigate development, angiogenesis, tumors, and to propagate and investigate
viruses or helminths.