Preferred Label : renal cortex interstitium;
Uberon definition : A compartment of the renal cortex situated between basement membranes of epithelia
and vessels that contains two contiguous cellular networks in mutual contact, one
formed by interstitial fibroblasts, the other by dendritic cells.;
Uberon synonym : kidney cortex interstitium; renal cortical interstitial tissue;
Uberon related term : cortical stroma;
Uberon Structure note : In the renal cortex, interstitial fibroblasts produce erythropoietin and are distinguished
from other interstitial cells by their prominent F-actin cytoskeleton, abundance of
rough endoplasmic reticulum, and by ecto-5'-nucleotidase expression in their plasma
membrane. The resident dendritic cells belong to the mononuclear phagocyte system
and fulfil a sentinel function. They are characterized by their expression of MHC
class II and CD11c.;
Origin ID : 0005270;
Automatic exact mappings (from CISMeF team)
- Uberon cross reference
- part of
A compartment of the renal cortex situated between basement membranes of epithelia
and vessels that contains two contiguous cellular networks in mutual contact, one
formed by interstitial fibroblasts, the other by dendritic cells.
