Uberon definition : The glomus forms from the splanchnic intermediate mesoderm and is the vascularized
filtration unit, filtering the blood before it enters the tubules. The glomus is external
to the nephron and extends over more than one body segment.;
Uberon synonym : glomerulus of pronephros;
Uberon related term : corpuscle; pronephric glomera; pronephric glomeruli; glomera; pronephric glomus;
Uberon narrow term : glomus;
Uberon Homology note : The teleost pronephros shares many essential features with the amphibian pronephros
including its derivation from mesoderm associated with the coelom and the derivation
of the glomerular blood supply from the medial dorsal aorta. However, unlike the pronephros
of amphibians, which have an external glomus and tubules with nephrostomes open to
the coelom, the mature teleost pronephros has no connection to the body cavity and
instead functions as a closed system (reference 1); This variation in nephron types
[with external glomeruli that open into the coelom and with internal glomeruli that
do not connect with the coelom] and their pattern of distribution suggest an evolutionary
sequence. Ancestral craniates probably had an external glomerulus and nephrostomes,
as do the first few to develop in very primitive craniates. (...) The mechanism would
become more efficient as the coelomic recess into which each glomerulus discharged
became a part of the tubule, that is, grew around the glomerulus as a renal capsule.
The glomerulus becomes internal. The nephrostomes were lost during subsequent evolution,
leaving the type of renal tubule found in most vertebrates (reference 2).[well established][VHOG];
The glomus forms from the splanchnic intermediate mesoderm and is the vascularized
filtration unit, filtering the blood before it enters the tubules. The glomus is external
to the nephron and extends over more than one body segment.
Automatic exact mappings (from CISMeF team)