Preferred Label : bursa of Fabricius;
Uberon definition : An epithelial and lymphoid organ that develops as a dorsal diverticulum of the proctodeal
region of the cloaca in birds. The luminal (interior) surface of the bursa is plicated
with as many as 15 primary and 7 secondary plicae or folds. These plicae have hundreds
of bursal follicles containing follicle-associated epithelial cells, lymphocytes,
macrophages, and plasma cells. Lymphoid stem cells migrate from the fetal liver to
the bursa during ontogeny. In the bursa, these stem cells acquire the characteristics
of mature, immunocompetent B cells[WP]. The bursa is an organ found in birds involved
in B cell differentiation[GO].;
Origin ID : 0003903;
Automatic exact mappings (from CISMeF team)
- Uberon cross reference
- has part
An epithelial and lymphoid organ that develops as a dorsal diverticulum of the proctodeal
region of the cloaca in birds. The luminal (interior) surface of the bursa is plicated
with as many as 15 primary and 7 secondary plicae or folds. These plicae have hundreds
of bursal follicles containing follicle-associated epithelial cells, lymphocytes,
macrophages, and plasma cells. Lymphoid stem cells migrate from the fetal liver to
the bursa during ontogeny. In the bursa, these stem cells acquire the characteristics
of mature, immunocompetent B cells[WP]. The bursa is an organ found in birds involved
in B cell differentiation[GO].
