Preferred Label : otic placode;
Uberon definition : A cranial placode which, once specified, invaginates to form an otic cup, which eventually
separates from the surface ectoderm to form the otic vesicle or otocyst, a rounded
structure without appar- ent polarity. As the otic placode invaginates into a cup
neuroblasts delaminate from the anterior ventral aspect of the otic epithelium to
give rise to neurons of the vestibulocochlear (statoacoustic) ganglion of cranial
nerve VIII[NBK];
Uberon related term : ear placode; octaval VIII placode; auditory placode; octaval placode; ear/otic placode;
Uberon Development note : With the exception of the pigment cells of the stria vascularis and the secretory
epithelium of the cochlea, which are of neural crest origin, all compo- nents of the
inner ear derive from the otic placode. In most species the thickening of the ectoderm
into a placode occurs in a region adjacent to rhombomere 5 (reviewed in Ohyama et
al., 2007), while in amphibians the otic placode is centered onto rhombomere 4 (Ruiz
i Altaba and Jessell, 1991).;
Uberon Homology note : We conclude this section by listing some of the many synapomorphies of craniates,
including (...) (2) neurogenic placodes (...).[well established][VHOG];
Origin ID : 0003069;
UMLS CUI : C1518677;
Currated CISMeF NLP mapping
- Semantic type(s)
- UMLS correspondences (same concept)
- Uberon cross reference
- Validated automatic mappings to NTBT
- develops into
- has part
- part of
A cranial placode which, once specified, invaginates to form an otic cup, which eventually
separates from the surface ectoderm to form the otic vesicle or otocyst, a rounded
structure without appar- ent polarity. As the otic placode invaginates into a cup
neuroblasts delaminate from the anterior ventral aspect of the otic epithelium to
give rise to neurons of the vestibulocochlear (statoacoustic) ganglion of cranial
nerve VIII[NBK]
