Uberon definition : A horseshoe-shaped thickening of the endoderm at the cranial (rostral) end of the
primitive streak formed by the involution of Spemann's organizer cells which, together
with the notochord, induces the formation of the neural plate from the overlying ectodermal
cells and contributes mesodermal type cells to the surrounding tissue;
Uberon broad term : head mesenchyme; head mesoderm;
Uberon Homology note : There are two opposing models that can potentially explain the differences in gsc
(goosecoid) expression between amphioxus and vertebrates. In one model, the vertebrate
gsc expression pattern more closely resembles the common ancestral state and the amphioxus
gsc expression pattern is a derivation associated with its unique morphology. (...)
In an alternate model, the amphioxus gsc expression pattern most closely represents
the common ancestral state and the vertebrate pattern is derived. This model suggests
that the evolution of vertebrates was accompanied by the segregation of gsc expression,
from a more general domain underlying the entire brain anlage to a distinct forebrain
organizer domain and subsequent prechordal plate. We feel this second model is more
parsimonious than the first model in that what would be novel anterior gsc expression
in vertebrates directly correlates with a novel vertebrate anterior structure, the
prechordal plate.[well established][VHOG];
A horseshoe-shaped thickening of the endoderm at the cranial (rostral) end of the
primitive streak formed by the involution of Spemann's organizer cells which, together
with the notochord, induces the formation of the neural plate from the overlying ectodermal
cells and contributes mesodermal type cells to the surrounding tissue