Uberon definition : A temporary epithelium that derives from the outer layer of the ectdoerm and is shed
once the inner layer differentiates to form a true epidermis.;
Uberon synonym : skin periderm;
Uberon related term : epidermis epithelial layer; epidermis outer layer; periderm; epitrichium; EVL;
Uberon Development note : In some mammals, Eyelid Fusion is thought to be driven by a population of cells which
are derived from the periderm, the outermost layer of the developing epidermis;
Uberon Taxon note : In mice, the first non-basal layer formed at E9.5; it is a temporary structure composed
of simple squamous epithelium that serves as the first barrier to the embryo's physical
environment, exists throughout the entire keratinocyte stratification process, and
sheds off at E17, when it is replaced by corneocytes[MP];