Preferred Label : median raphe nucleus;
Uberon definition : The median raphe nucleus (or superior central nucleus) is composed of polygonal, fusiform
and pyriform neurons and exists rostral to the nucleus raphe pontis. One trait of
the MRN is its inhibition by lysergic acid diethylamide and psilocin, two serotonin
antagonist hallucinogens. The inactivation of the nucleus centralis superior via LSD
produces a dose dependent inactivation in the MRN, but not in the raphe pallidus[WP,unvetted].;
Uberon synonym : superior central nucleus; median nucleus of the raphe; medial raphe nucleus; superior central nucleus raphe; cell group b8; superior central tegmental nucleus; MRN;
Origin ID : 0003004;
Automatic exact mappings (from CISMeF team)
- Uberon cross reference
- part of
The median raphe nucleus (or superior central nucleus) is composed of polygonal, fusiform
and pyriform neurons and exists rostral to the nucleus raphe pontis. One trait of
the MRN is its inhibition by lysergic acid diethylamide and psilocin, two serotonin
antagonist hallucinogens. The inactivation of the nucleus centralis superior via LSD
produces a dose dependent inactivation in the MRN, but not in the raphe pallidus[WP,unvetted].
