Preferred Label : medial dorsal nucleus of thalamus;
Uberon definition : The medial dorsal nucleus (or dorsomedial nucleus of thalamus) is a large nucleus
in the thalamus. It receives inputs from the Pre-Frontal Cortex and the Limbic System
and in turn relays them to the Pre-Frontal Association Cortex. As a result, it plays
a crucial role in attention, planning, organization, abstract thinking, multi-tasking
and active memory. The connections of the medial dorsal nucleus have even been used
to delineate the prefrontal cortex of the Göttingen minipig brain. By stereology the
number of brain cells in the region has been estimated to around 6.43 million neurons
in the adult human brain and 36.3 million glial cells, and with the newborn having
quite different numbers: around 11.2 million neurons and 10.6 million glial cells.
Lesions of the medial dorsal nucleus have been associated with Wernicke's encephalopathy
[WP,unvetted].;
Uberon synonym : mediodorsal nucleus of thalamus; medial dorsal thalamic nucleus; dorsal medial nucleus of thalamus; dorsomedial nucleus of thalamus; medial nuclear group of thalamus; nucleus dorsomedialis thalami; mediodorsal thalamic nucleus;
Uberon related term : medial group of the dorsal thalamus; mediodorsal nucleus of the thalamus; dorsal thalamus medial division; medial thalamic nuclear group;
Uberon broad term : medial dorsal nucleus; nucleus medialis dorsalis; mediodorsal nucleus; medial nuclear group; medial thalamic nucleus; dorsomedial nucleus; dorsomedial nuclear group; medial thalamic nuclei;
Origin ID : 0002739;
UMLS CUI : C0228329;
Automatic exact mappings (from CISMeF team)
- Semantic type(s)
- UMLS correspondences (same concept)
- Uberon cross reference
- has part
The medial dorsal nucleus (or dorsomedial nucleus of thalamus) is a large nucleus
in the thalamus. It receives inputs from the Pre-Frontal Cortex and the Limbic System
and in turn relays them to the Pre-Frontal Association Cortex. As a result, it plays
a crucial role in attention, planning, organization, abstract thinking, multi-tasking
and active memory. The connections of the medial dorsal nucleus have even been used
to delineate the prefrontal cortex of the Göttingen minipig brain. By stereology the
number of brain cells in the region has been estimated to around 6.43 million neurons
in the adult human brain and 36.3 million glial cells, and with the newborn having
quite different numbers: around 11.2 million neurons and 10.6 million glial cells.
Lesions of the medial dorsal nucleus have been associated with Wernicke's encephalopathy
[WP,unvetted].
