Preferred Label : meninx;
Uberon definition : Membrane organ that surrounds the brain and the spinal cord.;
Uberon synonym : meningeal layer; layer of meninges;
Uberon narrow term : meninx primitiva;
Uberon Homology note : In fishes, the meninges consist of a single membrane, the primitive meninx, wrapped
around the brain and spinal cord. With the adoption of terrestrial life, the meninges
doubled. In amphibians, reptiles, and birds, the meninges include a thick outer dura
mater derived from mesoderm and a thin inner secondary meninx. (...) In mammals, the
dura mater persists, but division of the secondary meninx yields both the arachnoid
and the pia mater from ectomesoderm.[well established][VHOG];
Uberon Taxon note : Whereas cyclostomes and fishes only have a single envelope called the primitive meninx,
amphibians have two layers, consisting of an outer dura mater which is extremely dense
and protective, and a pia-arachnoid or secondary meninx which is more delicate and
vascular. Mammals have three meninges: pia mater (which follows all the convolutions
of the brain and is the most interior), the arachnoid layer (which is delicate and
sends strands to the pia mater), and the dura mater (the outer, more protective meninx).;
Origin ID : 0002360;
UMLS CUI : C0025285;
Automatic exact mappings (from CISMeF team)
Semantic type(s)
UMLS correspondences (same concept)
Uberon cross reference
develops from
immediate transformation of
part of
Membrane organ that surrounds the brain and the spinal cord.