Preferred Label : gigantocellular nucleus;
Uberon definition : Nucleus located in the rostral ventrolateral medulla. The PGL was originally identified
by cytoarchitectural criteria in the human medulla (Olszewski and Baxter, 1954). In
humans, the PGL is located in the ventrolateral quadrant of the rostral medullary
tegmentum between the nucleus subtrigeminalis caudally, trapezoid body and the superior
olive rostrally, nucleus gigantocellularis medially, spinothalamic tract fibers laterally,
inferior olive ventrally, and the nucleus ambiguous dorsally (Olszewski and Baxter,
1954). In the rat, the PGL has been further subdivided into retrofacial PGL (caudal
to the facial nucleus), and more rostrally located juxtafacial PGL (medial to the
facial nucleus), based upon different connectivity.;
Uberon synonym : gigantocellular reticular nucleus; gigantocellular group; gigantocellular reticular nuclei;
Uberon related term : nucleus reticularis gigantocellularis;
Origin ID : 0002155;
Automatic exact mappings (from CISMeF team)
- Uberon cross reference
Nucleus located in the rostral ventrolateral medulla. The PGL was originally identified
by cytoarchitectural criteria in the human medulla (Olszewski and Baxter, 1954). In
humans, the PGL is located in the ventrolateral quadrant of the rostral medullary
tegmentum between the nucleus subtrigeminalis caudally, trapezoid body and the superior
olive rostrally, nucleus gigantocellularis medially, spinothalamic tract fibers laterally,
inferior olive ventrally, and the nucleus ambiguous dorsally (Olszewski and Baxter,
1954). In the rat, the PGL has been further subdivided into retrofacial PGL (caudal
to the facial nucleus), and more rostrally located juxtafacial PGL (medial to the
facial nucleus), based upon different connectivity.
