" /> atrioventricular canal - CISMeF





Preferred Label : atrioventricular canal;

Uberon definition : The part of the heart connecting the atrium to the cardiac ventricle[ZFA]. In the developing heart, the constriction between the atrium and ventricle constitutes the atrial canal, and indicates the site of the future atrioventricular valves[WP].;

Uberon synonym : AV canal; atrio-ventricular canal; atrial canal; AVC;

Uberon related term : ependymal canal;

Uberon Development note : The right side of the AVC becomes the tricuspid valve whereas the left side of the AVC will become the bicuspid valve;

Uberon Function note : In the embryo, the atrioventricular canal delays the impulse from atrium to ventricle[PMID:22984480];

Uberon Homology note : The heart is the first organ to form and function in a vertebrate. (...) Septation of the AV canal is initiated with the formation of inferior and superior endocardial cushions in response to signaling from the overlying myocardium. (...) Analysis of zebrafish mutants with cardiovascular defects uncovered a previously unexpected level of conservation between zebrafish and human cardiovascular physiology.[uncertain][VHOG];

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The part of the heart connecting the atrium to the cardiac ventricle[ZFA]. In the developing heart, the constriction between the atrium and ventricle constitutes the atrial canal, and indicates the site of the future atrioventricular valves[WP].

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08/07/2025


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