" /> endocardial cushion - CISMeF





Preferred Label : endocardial cushion;

Uberon definition : The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves[GO]. Swellings of tissue present between the endocardial and myocardial cell layers that will give rise to the interstitial cells of the cardiac valves[ZFA].;

Uberon synonym : atrioventricular cushion; AV cushion; endocardial cushion tissue; cardiac cushion;

Uberon related term : atrioventricular canal cushion; endocardial cushions;

Uberon Homology note : (Cardiac valve formation in vertebrates) In response to a myocardial signal, endocardial cells at chamber boundaries take on a mesenchymal character, delaminate and migrate into the cardiac jelly. There, they form an endocardial cushion that is later remodelled into a valve.[well established][VHOG];

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The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves[GO]. Swellings of tissue present between the endocardial and myocardial cell layers that will give rise to the interstitial cells of the cardiac valves[ZFA].

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03/05/2025


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