Preferred Label : tuberomammillary nucleus;
Uberon definition : The tuberomammillary nucleus is a subnucleus of the posterior third of the hypothalamus.
It consists of, largely, histaminergic and is involved with the control of arousal,
sleep and circadian rhythm. Axons of the tuberomammillary nucleus project primarily
to the cerebral cortex, thalamus, basal ganglia, basal forebrain, and hypothalamus.
The projections to the cerebral cortex directly increase cortical activation and arousal,
and projections to acetylcholinergic neurons of the basal forebrain and dorsal pons
do so indirectly, by increasing the release of acetylcholine in the cerebral cortex.
[WP,unvetted].;
Uberon synonym : caudal magnocellular nucleus; tuberomammillary hypothalamic nucleus; mammilloinfundibular nucleus; mammiloinfundibular nucleus;
Uberon related term : ventral tuberomammillary nucleus; tubero-mamillary area; tuberomammillary nucleus, ventral part; tuberomamillary nucleus; TM;
Uberon broad term : TM;
Origin ID : 0001936;
Automatic exact mappings (from CISMeF team)
- Uberon cross reference
- has part
- part of
The tuberomammillary nucleus is a subnucleus of the posterior third of the hypothalamus.
It consists of, largely, histaminergic and is involved with the control of arousal,
sleep and circadian rhythm. Axons of the tuberomammillary nucleus project primarily
to the cerebral cortex, thalamus, basal ganglia, basal forebrain, and hypothalamus.
The projections to the cerebral cortex directly increase cortical activation and arousal,
and projections to acetylcholinergic neurons of the basal forebrain and dorsal pons
do so indirectly, by increasing the release of acetylcholine in the cerebral cortex.
[WP,unvetted].
