Preferred Label : zona incerta;
Uberon definition : The zona incerta is a horizontally elongated region of gray matter cells in the subthalamus
below the thalamus. Its connections project extensively over the brain from the cerebral
cortex down into the spinal cord. Its function is unknown though several have been
proposed related to 'limbic-motor integration' such as controlling visceral activity
and pain; gating sensory input and synchronizing cortical and subcortical brain rhythms.
Its dysfunction may play a role in central pain syndrome. It is also been identified
as a promising deep brain stimulation therapy target for treating Parkinsons Disease.
Its existence was first described by Auguste Forel in 1877 as a 'region of which nothing
certain can be said'. A hundred and thirty years later in 2007, Nadia Urbain and Martin
Deschênes of Université Laval noted that the 'zona incerta is among the least studied
regions of the brain; its name does not even appear in the index of many textbooks.
' [WP,unvetted].;
Uberon related term : nucleus of the zona incerta; zona incerta proper;
Origin ID : 0001907;
Automatic exact mappings (from CISMeF team)
Uberon cross reference
has part
The zona incerta is a horizontally elongated region of gray matter cells in the subthalamus
below the thalamus. Its connections project extensively over the brain from the cerebral
cortex down into the spinal cord. Its function is unknown though several have been
proposed related to 'limbic-motor integration' such as controlling visceral activity
and pain; gating sensory input and synchronizing cortical and subcortical brain rhythms.
Its dysfunction may play a role in central pain syndrome. It is also been identified
as a promising deep brain stimulation therapy target for treating Parkinsons Disease.
Its existence was first described by Auguste Forel in 1877 as a 'region of which nothing
certain can be said'. A hundred and thirty years later in 2007, Nadia Urbain and Martin
Deschênes of Université Laval noted that the 'zona incerta is among the least studied
regions of the brain; its name does not even appear in the index of many textbooks.
' [WP,unvetted].