Uberon definition : The most anterior region the brain including both the telencephalon and diencephalon.;
Uberon related term : prosencephalon;
Uberon broad term : FB;
Uberon Homology note : In craniate embryos, neural expression of Distal-less-related genes is exclusively
in the forebrain (...). Because the major neural expression domain of amphioxus AmphiDll
is in the anterior three-fourths of the cerebral vesicle, we suggest that this region
of the neural tube is homologous to parts of the craniate forebrain. This conclusion
is strongly supported by three-dimensional, computer-assisted reconstruction of the
neural tube of amphioxus based on serial transmission electron microscopy. At the
neuroanatomical level, a number of detailed homologies are indicated between the anterior
three-fourths of the amphioxus cerebral vesicle and the diencephalic region of the
craniate forebrain. If one assumes that the amphioxus condition fairly represents
the nervous system of the proximate ancestor of the craniates, one can suggest that
they evolved from a creature that had the beginnings of a forebrain.[well established][VHOG];