Preferred Label : auditory ossicle bone;
Uberon definition : One of 3 small bones contained within the middle ear space and serve to transmit sounds
from the air to the fluid-filled labyrinth. The absence of the auditory ossicles would
constitute a moderate-to-severe hearing loss. The term 'ossicles' literally means
'tiny bones' and commonly refers to the auditory ossicles, though the term may refer
to any small bone throughout the body. [WP,unvetted].;
Uberon synonym : auditory bone; middle ear ossicle;
Uberon related term : ear ossicle; ear ossicles; ear bone; middle ear bone; ossicle of ear; ossicular chain; ossicle of inner ear; auditory ossicle;
Uberon broad term : ossicle;
Uberon Development note : Studies have shown that ear bones in mammal embryos are attached to the dentary, which
is part of the jaw. These are ossified portions of cartilage -- called Meckel's cartilage
-- that are attached to the jaw. As the embryo develops, the cartilage hardens to
form bone. Later in development, the bone structure breaks loose from the jaw and
migrates to the inner ear area. The structure is known as the middle ear, and is made
up of the incus, stapes, malleus, and tympanic membrane. These correspond to the quadrate,
prearticular, articular, and angular structures in the reptile jaw. For this reason,
researchers believe the similarity of the results shows that mammals and reptiles
have a common ancestry.;
Uberon Homology note : Additional structural analysis within a phylogenetic context has led to the remarkable
discovery that in synapsids, thought to be ancestral to mammals, both the quadrate
and articular have become reduced and less firmly articulated with their surrounding
bones, reducing their jaw-joint-bearing role. This trend culminated with the incorporation
of the quadrate, the columella (which remains articulated with the quadrate), and
the articular into the expanded middle ear in mammals.[well established][VHOG];
Origin ID : 0001686;
UMLS CUI : C0013450;
Automatic exact mappings (from CISMeF team)
- Semantic type(s)
- UMLS correspondences (same concept)
- Uberon cross reference
- has part
- surrounded by
One of 3 small bones contained within the middle ear space and serve to transmit sounds
from the air to the fluid-filled labyrinth. The absence of the auditory ossicles would
constitute a moderate-to-severe hearing loss. The term 'ossicles' literally means
'tiny bones' and commonly refers to the auditory ossicles, though the term may refer
to any small bone throughout the body. [WP,unvetted].
