Uberon definition : the section of the renal tubule in the kidney medulla with a hairpin bend; consists
of a descending limb and an ascending limb, and is situated between the proximal convoluted
tubule to the distal convoluted tubule; it functions to reabsorb water and ions from
the urine;
Uberon synonym : Henle loop; Henle's loop;
Uberon Function note : The loop of Henle plays an important role in creating a concentration gradient in
the medulla of the kidney. It is involved in reabsorption of filtered water and ions
including sodium, potassium and calcium, and independently regulates both the volume
and osmolarity of body fluids.;
Uberon Taxon note : The structure differs considerably between species; there is a definite physical loop
of Henle in the mammalian and avian renal systems but this seems to be absent in Xenopus.
However, homologs of some, but not all, molecular markers (e.g. cldn8 and clcnk) of
the mammalian loop of Henle were found to be present in the pronephros of the frog
larva .;
the section of the renal tubule in the kidney medulla with a hairpin bend; consists
of a descending limb and an ascending limb, and is situated between the proximal convoluted
tubule to the distal convoluted tubule; it functions to reabsorb water and ions from
the urine