Uberon definition : The tail of the pancreas, located anatomically left near the hilum of the spleen,
is not simply an anatomical distinction. The tail is the only part of the pancreas
which contains Pancreatic Polypeptide (PP) cells, which are responsible for secreting
pancreatic polypeptide to coordinate exocrine and islet enzyme release. PP cells are
found in the tail's periphery. Beta cells and delta cells are found in the central
part of the tail as with the rest of the pancreas. The cells described above are located
exclusively in the islet cells; their secretions reach exocrine portions of the pancreas
via the capillary network surrounding the islet cell populations. [WP,unvetted].;
Uberon synonym : pancreatic tail; left extremity of pancreas; pancreas tail;
Uberon Homology note : Hagfish and lampreys may have one or more endocrine buds - and later the vertebrate
pancreas develop as independent ventral and dorsal buds that eventually fuse to become
one organ.[well established][VHOG];
The tail of the pancreas, located anatomically left near the hilum of the spleen,
is not simply an anatomical distinction. The tail is the only part of the pancreas
which contains Pancreatic Polypeptide (PP) cells, which are responsible for secreting
pancreatic polypeptide to coordinate exocrine and islet enzyme release. PP cells are
found in the tail's periphery. Beta cells and delta cells are found in the central
part of the tail as with the rest of the pancreas. The cells described above are located
exclusively in the islet cells; their secretions reach exocrine portions of the pancreas
via the capillary network surrounding the islet cell populations. [WP,unvetted].