Preferred Label : neural tube;
Uberon definition : In the developing vertebrate, the neural tube is the embryo's precursor to the central
nervous system, which comprises the brain and spinal cord. The neural groove gradually
deepens as the neural folds become elevated, and ultimately the folds meet and coalesce
in the middle line and convert the groove into a closed tube, the neural tube or neural
canal (which strictly speaking is the center of the neural tube), the ectodermal wall
of which forms the rudiment of the nervous system. [WP,unvetted].;
Uberon related term : presumptive central nervous system; neural primordium;
Uberon Development note : The mature structure of the neural tube exists when the tube has been segmented into
the forebrain, midbrain, hindbrain and spinal cord regions. In addition neural crest
has budded away from the epithelium;
Uberon Homology note : (...) at some stage of its development, every chordate exhibits five uniquely derived
characters or synapomorphies of the group: (...) (4) a single, tubular nerve cord
that is located dorsal to the notochord (...).[well established][VHOG];
Origin ID : 0001049;
UMLS CUI : C0231024;
Currated CISMeF NLP mapping
- Semantic type(s)
- UMLS correspondences (same concept)
- Uberon cross reference
- develops from
- develops into
- dorsal to
- has part
In the developing vertebrate, the neural tube is the embryo's precursor to the central
nervous system, which comprises the brain and spinal cord. The neural groove gradually
deepens as the neural folds become elevated, and ultimately the folds meet and coalesce
in the middle line and convert the groove into a closed tube, the neural tube or neural
canal (which strictly speaking is the center of the neural tube), the ectodermal wall
of which forms the rudiment of the nervous system. [WP,unvetted].
