Preferred Label : neurofibroma;
RADLEX synonyms : neurofibroma (WHO grade I);
Definition : A moderately firm, benign, encapsulated tumor resulting from proliferation of schwann
cells and fibroblasts that includes portions of nerve fibers. The tumors usually develop
along peripheral or cranial nerves and are a central feature of neurofibromatosis
1, where they may occur intracranially or involve spinal roots. Pathologic features
include fusiform enlargement of the involved nerve. Microscopic examination reveals
a disorganized and loose cellular pattern with elongated nuclei intermixed with fibrous
strands. (From Adams et al., Principles of Neurology, 6th ed, p1016) [MeSH];
UMLS CUI (RADLEX) : C0027830;
Origin ID : RID4462;
UMLS CUI : C0027830;
Associated condition of
- Automatic exact mappings (from CISMeF team)
- Currated CISMeF NLP mapping
- See also inter- (CISMeF)
- Semantic type(s)
- UMLS correspondences (same concept)
A moderately firm, benign, encapsulated tumor resulting from proliferation of schwann
cells and fibroblasts that includes portions of nerve fibers. The tumors usually develop
along peripheral or cranial nerves and are a central feature of neurofibromatosis
1, where they may occur intracranially or involve spinal roots. Pathologic features
include fusiform enlargement of the involved nerve. Microscopic examination reveals
a disorganized and loose cellular pattern with elongated nuclei intermixed with fibrous
strands. (From Adams et al., Principles of Neurology, 6th ed, p1016) [MeSH]
