Preferred Label : neuroblastoma;
RADLEX synonyms : Schwannian stroma-poor peripheral neuroblastic neoplasm;
Definition : A common neoplasm of early childhood arising from neural crest cells in the sympathetic
nervous system, and characterized by diverse clinical behavior, ranging from spontaneous
remission to rapid metastatic progression and death. This tumor is the most common
intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or
rarely occur in the central nervous system. Histologic features include uniform round
cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular
septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From
DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr
Opin Oncol 1998 Jan;10(1):43-51) [MeSH];
UMLS CUI (RADLEX) : C0027819;
Origin ID : RID4454;
UMLS CUI : C0027819;
Associated condition of
- Automatic exact mappings (from CISMeF team)
- Semantic type(s)
- UMLS correspondences (same concept)
A common neoplasm of early childhood arising from neural crest cells in the sympathetic
nervous system, and characterized by diverse clinical behavior, ranging from spontaneous
remission to rapid metastatic progression and death. This tumor is the most common
intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or
rarely occur in the central nervous system. Histologic features include uniform round
cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular
septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From
DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr
Opin Oncol 1998 Jan;10(1):43-51) [MeSH]
