Preferred Label : small cell carcinoma;
RADLEX synonyms : oat cell carcinoma;
Definition : An anaplastic, highly malignant, and usually bronchogenic carcinoma composed of small
ovoid cells with scanty neoplasm. It is characterized by a dominant, deeply basophilic
nucleus, and absent or indistinct nucleoli. There are admixtures of small cell lung
carcinoma with other types of lung cancer. Small cell carcinomas are distinguished
by their distinctive biological features, response to chemotherapy and radiotherapy,
and by their nearly universal tendency to develop overt or subclinical metastases,
which frequently eliminates surgery in most patients. (From Stedman, 25th ed; Holland
et al., Cancer Medicine, 3d ed, p1286-7) [MeSH];
UMLS CUI (RADLEX) : C0149925;
Origin ID : RID4256;
UMLS CUI : C0262584;
Automatic exact mappings (from CISMeF team)
- Currated CISMeF NLP mapping
- Semantic type(s)
- UMLS correspondences (same concept)
An anaplastic, highly malignant, and usually bronchogenic carcinoma composed of small
ovoid cells with scanty neoplasm. It is characterized by a dominant, deeply basophilic
nucleus, and absent or indistinct nucleoli. There are admixtures of small cell lung
carcinoma with other types of lung cancer. Small cell carcinomas are distinguished
by their distinctive biological features, response to chemotherapy and radiotherapy,
and by their nearly universal tendency to develop overt or subclinical metastases,
which frequently eliminates surgery in most patients. (From Stedman, 25th ed; Holland
et al., Cancer Medicine, 3d ed, p1286-7) [MeSH]
