Preferred Label : polymyositis;
Definition : Diseases characterized by inflammation involving multiple muscles. This may occur
as an acute or chronic condition associated with medication toxicity (drug toxicity);
connective tissue diseases; infections; malignant neoplasms; and other disorders.
The term polymyositis is frequently used to refer to a specific clinical entity characterized
by subacute or slowly progressing symmetrical weakness primarily affecting the proximal
limb and trunk muscles. The illness may occur at any age, but is most frequent in
the fourth to sixth decade of life. Weakness of pharyngeal and laryngeal muscles,
interstitial lung disease, and inflammation of the myocardium may also occur. Muscle
biopsy reveals widespread destruction of segments of muscle fibers and an inflammatory
cellular response. (Adams et al., Principles of Neurology, 6th ed, pp1404-9) [MeSH];
UMLS CUI (RADLEX) : C0085655;
Origin ID : RID3654;
UMLS CUI : C0085655;
Associated condition of
- Automatic exact mappings (from CISMeF team)
- Currated CISMeF NLP mapping
- Semantic type(s)
- UMLS correspondences (same concept)
Diseases characterized by inflammation involving multiple muscles. This may occur
as an acute or chronic condition associated with medication toxicity (drug toxicity);
connective tissue diseases; infections; malignant neoplasms; and other disorders.
The term polymyositis is frequently used to refer to a specific clinical entity characterized
by subacute or slowly progressing symmetrical weakness primarily affecting the proximal
limb and trunk muscles. The illness may occur at any age, but is most frequent in
the fourth to sixth decade of life. Weakness of pharyngeal and laryngeal muscles,
interstitial lung disease, and inflammation of the myocardium may also occur. Muscle
biopsy reveals widespread destruction of segments of muscle fibers and an inflammatory
cellular response. (Adams et al., Principles of Neurology, 6th ed, pp1404-9) [MeSH]
