Preferred Label : acute disseminated encephalomyelitis;
RADLEX synonyms : ADEM;
Definition : An acute or subacute inflammatory process of the central nervous system characterized
histologically by multiple foci of perivascular demyelination. Symptom onset usually
occurs several days after an acute viral infection or immunization, but it may coincide
with the onset of infection or rarely no antecedent event can be identified. Clinical
manifestations include confusion, somnolence, fever, nuchal rigidity, and involuntary
movements. The illness may progress to coma and eventually be fatal. (Adams et al.,
Principles of Neurology, 6th ed, p921) [MeSH];
UMLS CUI (RADLEX) : C0014059;
Origin ID : RID3415;
UMLS CUI : C0014059;
Currated CISMeF NLP mapping
Semantic type(s)
UMLS correspondences (same concept)
An acute or subacute inflammatory process of the central nervous system characterized
histologically by multiple foci of perivascular demyelination. Symptom onset usually
occurs several days after an acute viral infection or immunization, but it may coincide
with the onset of infection or rarely no antecedent event can be identified. Clinical
manifestations include confusion, somnolence, fever, nuchal rigidity, and involuntary
movements. The illness may progress to coma and eventually be fatal. (Adams et al.,
Principles of Neurology, 6th ed, p921) [MeSH]