Aurora Kinase B

Preferred Label : Aurora Kinase B;

NCIt synonyms : Aurora-B; Aurora Kinase B Protein; Aurora/IPL1-Related Kinase; STK-1; Serine-Threonine Kinase-12; AIM-1; Serine/Threonine Protein Kinase 12; Aurora-1; Aurora B; Serine/Threonine-Protein Kinase 5; Serine/Threonine-Protein Kinase 12; Aurora/IPL1-Related Kinase 2; Aurora- and IPL1-Like Midbody-Associated Protein 1; Aurora-Related Kinase 2; ARK-2; Aurora 1; EC 2.7.11.1; Serine/Threonine-Protein Kinase Aurora-B;

NCIt definition : Aurora kinase B (344 aa, 39 kDa) is encoded by the human AURKB gene. This protein plays a role in both the modulation of microtubule structure and facilitation of chromosome segregation during mitosis and meiosis.; Aurora kinase B (344 aa, 39 kDa) is encoded by the human AURKB gene. This protein plays a role in both the modulation of microtubule structure and facilitation of chromosome segregation during mitosis and meiosis.;

Details

Origin ID

C68596;

UMLS CUI

C3711547;

Automatic exact mappings (from CISMeF team)
- Aurora kinase b [OMIM gene]
- Crystallin beta-gamma domain-containing protein 1 [OMIM gene]
- Cyclin-dependent kinase 7 [OMIM gene]
- Fms-related tyrosine kinase 3 [OMIM gene]
- Solute carrier family 45, member 2 [OMIM gene]
- aurora kinase B [MeSH Descriptor]
- aurora kinase B [MeSH concept]
- aurora kinase B [HGNC gene]
- fms related receptor tyrosine kinase 3 [ORDO Gene]
- pyruvate dehydrogenase (acetyl-transferring) kinase activity [GO term]
- solute carrier family 45 member 2 [ORDO Gene]
OMIM relation
- Aurora kinase b [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- AURKB protein, human [MeSH concept]
- AURKB protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- AURKB Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- Serine/Threonine Protein Kinase Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_biochemical_function
- Kinase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Aurora A Signaling Pathway [NCIt concept]
- Aurora B Signaling Pathway [NCIt concept]
- Aurora C Signaling Pathway [NCIt concept]
- Aurora Kinase Signaling Pathway [NCIt concept]
- FOXM1 Transcription Factor Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Cycle Regulation Process [NCIt concept]
- Cytokinesis [NCIt concept]
- Cytoskeletal Modeling [NCIt concept]
- Mitosis [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Protein Phosphorylation Process [NCIt concept]
- Serine/Threonine Phosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]
is_target
- Aurora B Serine/Threonine Kinase Inhibitor TAK-901 [NCIt concept]
- Aurora B/VEGFR/FGFR Inhibitor AL8326 [NCIt concept]
- Barasertib [NCIt concept]
- Cenisertib [NCIt concept]
- Danusertib [NCIt concept]
- Defosbarasertib [NCIt concept]
- Ibcasertib [NCIt concept]
- Ilorasertib [NCIt concept]
- Tinengotinib [NCIt concept]
- Tozasertib Lactate [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients