KIAA1549/BRAF Fusion Gene

Preferred Label : KIAA1549/BRAF Fusion Gene;

NCIt synonyms : KIAA1549-BRAF Fusion Gene; BRAF/KIAA1549 Fusion Gene; KIAA1549::BRAF Fusion Gene;

NCIt definition : A fusion gene that results from a tandem duplication of approximately 2 Mb at 7q34 which fuses exon 15 or 16 of the KIAA1549 gene to exon 9 or 11 of the BRAF gene. This fusion is associated with pilocytic astrocytoma.;

NCI Metathesaurus CUI : CL433552;

PubMed : 18974108;

Details

Origin ID

C99843;

UMLS CUI

C2681629;

Automatic exact mappings (from CISMeF team)
- B-raf protooncogene, serine/threonine kinase [OMIM gene]
- Kiaa1549 gene [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
UMLS correspondences (same concept)
- KIAA1549 [HGNC gene]
- Kiaa1549 gene [OMIM gene]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- KIAA1549/BRAF Fusion Protein [NCIt concept]
gene_involved_in_molecular_abnormality
- KIAA1549-BRAF Fusion Protein Expression [NCIt concept]
gene_involved_in_pathogenesis_of_disease
- Diffuse Leptomeningeal Glioneuronal Tumor [NCIt concept]
gene_mapped_to_disease
- Diffuse Leptomeningeal Glioneuronal Tumor [NCIt concept]
gene_plays_role_in_process
- Signal Transduction [NCIt concept]
- Tyrosine Phosphorylation [NCIt concept]
related_to_genetic_biomarker
- BRAF Gene [NCIt concept]
- KIAA1549 Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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